Description

1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-1-(Trimethylsilyl)- is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is specifically engineered to serve as a key intermediate in the development of complex pharmaceutical and agrochemical molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its unique fused-ring structure.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology: Employed in the design and synthesis of molecular probes and labeled compounds for biochemical and pharmacological studies.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form new carbon-carbon bonds.
• Organometallic Chemistry: Acts as a ligand precursor or a functionalized scaffold in the preparation of metal-organic complexes.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-1-(Trimethylsilyl)-
CAS No.	934388-23-5
Molecular Formula	C10H13BrN2Si
Molecular Weight	269.22 g/mol
Synonyms	4-Bromo-1-(trimethylsilyl)-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-1-(trimethylsilyl)-7-azaindole; 4-Bromo-1-TMS-7-azaindole; 1-(Trimethylsilyl)-4-bromo-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-1H-pyrrolo[2,3-b]pyridine, 1-(trimethylsilyl)- derivative; 7-Azaindole, 4-bromo-1-(trimethylsilyl)-; TMS-4-Bromo-7-azaindole
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-1-(Trimethylsilyl)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality systems are designed to meet the stringent requirements of advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.