Description

1H-Pyrrolo[2,3-B]Pyridine, 4-Iodo-1-(Trimethylsilyl)- is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring precise molecular architecture in complex organic syntheses. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of novel active ingredients and in advanced materials science for creating specialized functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Acts as a building block for organic semiconductors, ligands for catalysis, and other functional organic materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form new carbon-carbon bonds.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and tags for studying biological systems.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-Iodo-1-(Trimethylsilyl)-
CAS No.	934388-22-4
Molecular Formula	C10H13IN2Si
Molecular Weight	316.21 g/mol
Synonyms	4-Iodo-1-(trimethylsilyl)-1H-pyrrolo[2,3-b]pyridine; 1-(Trimethylsilyl)-4-iodo-1H-pyrrolo[2,3-b]pyridine; 4-Iodo-1H-pyrrolo[2,3-b]pyridine, 1-(trimethylsilyl)-; 1H-Pyrrolo[2,3-b]pyridine, 4-iodo-1-(trimethylsilyl)-; 4-Iodo-1-TMS-7-azaindole; 7-Azaindole, 4-iodo-1-(trimethylsilyl)-; TMS-4-Iodo-7-azaindole; 4-Iodo-1-trimethylsilyl-7-azaindole
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 4-Iodo-1-(Trimethylsilyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment. We adhere to cGMP principles for pharmaceutical-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.