Description

3-Pyridinecarboxaldehyde, 2-Chloro-5-(Trifluoromethyl)- is a high-value, multi-functional heterocyclic building block characterized by its pyridine core, chloro, and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique structure imparts desirable biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced crop protection agents, and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethylpyridine moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Useful for creating labeled compounds and probes for studying biological mechanisms.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Pyridinecarboxaldehyde, 2-Chloro-5-(Trifluoromethyl)-
CAS No.	934279-60-4
Molecular Formula	C7H3ClF3NO
Molecular Weight	209.55 g/mol
Synonyms	2-Chloro-5-(trifluoromethyl)nicotinaldehyde; 2-Chloro-5-(trifluoromethyl)pyridine-3-carboxaldehyde; 3-Formyl-2-chloro-5-(trifluoromethyl)pyridine; 2-Chloro-5-trifluoromethyl-3-pyridinecarboxaldehyde; 2-Chloro-5-(trifluoromethyl)-3-pyridinecarbaldehyde; 2-Chloro-5-(trifluoromethyl)pyridine-3-carbaldehyde; 2-Chloro-5-(trifluoromethyl)-3-pyridylcarboxaldehyde
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-5-(Trifluoromethyl)nicotinaldehyde adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.