Description

5-(2, 4-Difluorophenyl)-Isoxazole-3-Carboxylic Acid Ethyl Ester is a high-value fluorinated isoxazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile, functionalized scaffold for constructing complex molecules with tailored biological and material properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluorophenyl and isoxazole motifs.
• Material Science Research: Serves as a precursor for synthesizing specialized polymers, liquid crystals, or organic electronic materials due to its aromatic and heterocyclic structure.
• Chemical Biology Probe Development: Employed in creating molecular probes and tool compounds for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-(2, 4-Difluorophenyl)-Isoxazole-3-Carboxylic Acid Ethyl Ester
CAS No.	934188-80-4
Molecular Formula	C12H9F2NO3
Molecular Weight	253.20 g/mol
Synonyms	Ethyl 5-(2,4-difluorophenyl)isoxazole-3-carboxylate; 5-(2,4-Difluorophenyl)-3-(ethoxycarbonyl)isoxazole; 3-Carbethoxy-5-(2,4-difluorophenyl)isoxazole; 934188-80-4; 5-(2,4-Difluorophenyl)isoxazole-3-carboxylic acid ethyl ester; AI3-63573; SCHEMBL2180210; ZINC000095254756
EINECS	Contact for details

Quality Control

Our 5-(2, 4-Difluorophenyl)-Isoxazole-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; ensure containers are sealed under inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.