Description

1-(Thien-2-Ylsulfonyl)Piperidin-4-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its sulfonamide-linked thiophene and piperidine amine structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Protease Inhibitor Development: Serves as a core scaffold for designing inhibitors of specific enzymes.
• Kinase Inhibitor Synthesis: Employed in the creation of small molecule inhibitors for kinase targets relevant in cancer research.
• Chemical Biology Probes: Utilized to develop tool compounds for studying biological processes and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes for clients.

Basic Information

Product Name	1-(Thien-2-Ylsulfonyl)Piperidin-4-Amine
CAS No.	934063-82-8
Molecular Formula	C9H12N2O2S2
Molecular Weight	244.33 g/mol
Synonyms	1-(Thiophen-2-ylsulfonyl)piperidin-4-amine; 4-Amino-1-(thiophen-2-ylsulfonyl)piperidine; 1-(2-Thienylsulfonyl)-4-piperidinamine; 4-Piperidinamine, 1-(2-thienylsulfonyl)-; Piperidin-4-amine, 1-(thien-2-ylsulfonyl)-; 934063-82-8; 1-(Thien-2-Ylsulfonyl)Piperidin-4-Amine
EINECS	Contact for details

Quality Control

Our 1-(Thien-2-Ylsulfonyl)Piperidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. For custom synthesis projects, our quality protocols are aligned with current Good Manufacturing Practice (cGMP) principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.