Description

6,11-Dihydro-5H-Dipyrido[2,3-B:4',3'-F]-Azepin-5-One is a high-purity, advanced pharmaceutical intermediate with the CAS number 933768-16-2. This heterocyclic compound is valued for its complex fused-ring structure, which serves as a critical building block in modern medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

This specialized intermediate is designed for high-value synthesis and research applications, including:

• Pharmaceutical Research & Development: A key precursor in the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of target molecules for preclinical and clinical studies.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for investigating novel heterocyclic chemistry and reaction pathways.

Basic Information

Product Name	6,11-Dihydro-5H-Dipyrido[2,3-B:4',3'-F]-Azepin-5-One
CAS No.	933768-16-2
Molecular Formula	C14H11N3O
Molecular Weight	237.26 g/mol
Synonyms	6,11-Dihydro-5H-dipyrido[2,3-b:4',3'-f]azepin-5-one; 5H-Dipyrido[2,3-b:4',3'-f]azepin-5-one, 6,11-dihydro-; Dipyridoazepinone derivative; AZD-1283 Intermediate (related research compound); Tricyclic fused diazepinone
EINECS	Contact for details

Quality Control

Our 6,11-Dihydro-5H-Dipyrido[2,3-B:4',3'-F]-Azepin-5-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% to ≥98% by HPLC), related substances, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.