Description

cis-Octahydrofuro[3,4-C]Pyridine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex fused bicyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is primarily sought by pharmaceutical R&D laboratories, contract development and manufacturing organizations (CDMOs), and fine chemical suppliers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new molecules with improved efficacy and safety profiles.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Academic & Institutional Research: Employed in universities and research institutes for studying heterocyclic chemistry and developing new synthetic methodologies.
• Contract Manufacturing: Supplied to CDMOs for the production of clinical trial materials and commercial APIs for niche therapeutic areas.

Basic Information

Product Name	cis-Octahydrofuro[3,4-C]Pyridine Hydrochloride
CAS No.	933688-11-0
Molecular Formula	C9H16ClNO
Molecular Weight	189.68 g/mol
Synonyms	cis-Octahydrofuro[3,4-c]pyridine HCl; (3aR,6aS)-Octahydrofuro[3,4-c]pyridine hydrochloride; Furo[3,4-c]pyridine, octahydro-, hydrochloride, cis-; 1,2,3,3a,4,5,6,6a-Octahydrofuro[3,4-c]pyridine hydrochloride; cis-1,2,3,3a,4,5,6,6a-Octahydrofuro[3,4-c]pyridine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of cis-Octahydrofuro[3,4-C]Pyridine Hydrochloride is manufactured and tested to meet stringent quality standards suitable for pharmaceutical development. Our quality assurance protocol includes identity confirmation, purity assay, and control of specific impurities to ensure batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.