Description

Methyl 3-Bromo-5-Chlorobenzoate is a high-purity organic building block and key synthetic intermediate. This compound is valued for its precise halogen substitution pattern, which enables selective functionalization in complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of advanced active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring specific halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the bromo and chloro substituents are key for bioactivity.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Buchwald-Hartwig aminations, enabling carbon-carbon and carbon-heteroatom bond formation.
• Chemical Library Development: Employed in medicinal and combinatorial chemistry for the generation of diverse compound libraries for high-throughput screening.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	Methyl 3-Bromo-5-Chlorobenzoate
CAS No.	933585-58-1
Molecular Formula	C8H6BrClO2
Molecular Weight	249.49 g/mol
Synonyms	3-Bromo-5-chlorobenzoic acid methyl ester; Methyl 3-bromo-5-chlorobenzoate; Benzoic acid, 3-bromo-5-chloro-, methyl ester; 3-Bromo-5-chloro-benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-5-Chlorobenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment supports applications in regulated environments, including cGMP for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.