Description

(R)-Methyl 1-p-Tolylaziridine-2-Carboxylate is a high-value, chiral aziridine derivative serving as a critical building block in asymmetric synthesis. This compound is essential for constructing complex molecular architectures with precise stereochemical control, enabling the development of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of novel, stereoselective pesticides and herbicides with improved efficacy and environmental profiles.
• Ligand & Catalyst Precursor: Employed in the preparation of chiral ligands and organocatalysts for asymmetric transformations like epoxide ring-opening and cycloaddition reactions.
• Academic & Process Chemistry: A valuable tool for methodological development in organic synthesis and for studying stereoselective reaction mechanisms.
• Fine Chemical Synthesis: Building block for creating complex natural product analogs and other high-value specialty chemicals.

Basic Information

Product Name	(R)-Methyl 1-p-Tolylaziridine-2-Carboxylate
CAS No.	933453-56-6
Molecular Formula	C12H15NO2
Molecular Weight	205.25 g/mol
Synonyms	(R)-Methyl 1-(4-methylphenyl)aziridine-2-carboxylate; Methyl (2R)-1-(4-methylphenyl)aziridine-2-carboxylate; (R)-1-p-Tolylaziridine-2-carboxylic acid methyl ester; (R)-Methyl 1-(p-tolyl)aziridine-2-carboxylate; Aziridine-2-carboxylic acid, 1-(4-methylphenyl)-, methyl ester, (2R)-; (R)-1-(4-Methylphenyl)aziridine-2-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Every batch of (R)-Methyl 1-p-Tolylaziridine-2-Carboxylate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is supplied with each shipment to guarantee reproducible performance and supply chain integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.