Description

n-(2-Chloro-Pyridin-3-Yl)-2-Trifluoromethyl-Benzamide CAS NO 933037-23-1 is a high-purity, specialized organic compound featuring a benzamide core substituted with a chloropyridine and a trifluoromethyl group. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its unique structure is designed to impart specific biological activity and physicochemical properties to target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Research: Serves as a precursor for developing new generation pesticides and herbicides, leveraging the biological activity of the pyridine and benzamide motifs.
• Medicinal Chemistry: Used extensively in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical space.
• Chemical Biology Probe: Employed in the development of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• Material Science Research: Investigated as a potential monomer or additive for creating specialty polymers with unique properties.

Basic Information

Item	Detail
Product Name	n-(2-Chloro-Pyridin-3-Yl)-2-Trifluoromethyl-Benzamide
CAS No.	933037-23-1
Molecular Formula	C13H8ClF3N2O
Molecular Weight	300.66 g/mol
Synonyms	2-Trifluoromethyl-N-(2-chloropyridin-3-yl)benzamide; N-(2-Chloro-3-pyridinyl)-2-(trifluoromethyl)benzamide; 2-Chloro-N-(2-(trifluoromethyl)benzoyl)nicotinamide; Benzamide, N-(2-chloro-3-pyridinyl)-2-(trifluoromethyl)-; 933037-23-1; 2-Chloropyridine-3-carboxamide, N-(2-(trifluoromethyl)phenyl)-; 3-Pyridinecarboxamide, 2-chloro-N-[2-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our n-(2-Chloro-Pyridin-3-Yl)-2-Trifluoromethyl-Benzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ICH guidelines ensure a reliable supply of high-grade material for your most demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.