Description

2,4,5-Trifluorophenyl Isocyanate is a versatile and highly reactive aromatic isocyanate building block, essential for introducing the 2,4,5-trifluorophenyl moiety into complex molecules. Its primary value lies in its role as a key intermediate in the synthesis of advanced pharmaceutical compounds and agrochemicals, where the trifluoromethyl and isocyanate groups enable precise molecular design. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing specialized polyurethanes, coatings, and adhesives with enhanced chemical resistance.
• Liquid Crystal & OLED Materials: Employed in the synthesis of fluorinated compounds for electronic display and lighting applications.
• Chemical Research & Development: A valuable reagent for academic and industrial research in organic synthesis and medicinal chemistry.
• Dye & Pigment Intermediate: Used in the creation of specialized fluorinated dyes and pigments.

Basic Information

Product Name	2,4,5-Trifluorophenyl Isocyanate
CAS No.	932710-67-3
Molecular Formula	C7H3F3NO
Molecular Weight	180.10 g/mol
Synonyms	2,4,5-Trifluorophenyl isocyanate; 1-Isocyanato-2,4,5-trifluorobenzene; 2,4,5-Trifluorobenzene isocyanate; (2,4,5-Trifluorophenyl)carbimidoic acid; Isocyanic acid, 2,4,5-trifluorophenyl ester
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluorophenyl Isocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.