Description

1H-Pyrrolo[2,3-B]Pyridine, 6-Chloro-3-(Trifluoromethyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of innovative small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a precursor in the synthesis of novel pesticides and herbicides, leveraging the biological activity of the pyrrolopyridine scaffold.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex heterocyclic molecules due to its reactive chloro and trifluoromethyl functional groups.
• Material Science: Investigated for the development of specialty chemicals and functional materials, including organic semiconductors and ligands for catalysis.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 6-Chloro-3-(Trifluoromethyl)-
CAS No.	932406-36-5
Molecular Formula	C8H4ClF3N2
Molecular Weight	220.58 g/mol
Synonyms	6-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-3-(trifluoromethyl)-7-azaindole; 6-Chloro-3-trifluoromethyl-1H-pyrrolo[2,3-b]pyridine; 3-Trifluoromethyl-6-chloro-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 6-chloro-3-(trifluoromethyl)-; 932406-36-5
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 6-Chloro-3-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.