Description

(1R)- 6,6'-Bis(3,5-Dimethylphenyl)-2,2',3,3'-Tetrahydro-1,1'-Spirobi[1H-Indene]-7,7'-Diol is a high-purity, chiral spirobiindane derivative that serves as a sophisticated ligand and building block in advanced chemical synthesis. Its value lies in its rigid, three-dimensional structure and specific stereochemistry, which are critical for inducing enantioselectivity in catalytic reactions and for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise chiral control for developing new active ingredients and high-performance materials.

Application

• Asymmetric Catalysis: Employed as a chiral ligand or precursor for ligands in transition metal-catalyzed reactions, such as hydrogenation, cross-coupling, and C-H activation.
• Pharmaceutical Intermediates: A key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) for therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Material Science: Serves as a monomer or core structure for developing chiral polymers, liquid crystals, or advanced organic frameworks (MOFs/COFs).
• Academic & Industrial R&D: A valuable tool for chemists exploring new methodologies in organic synthesis and catalysis.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	(1R)- 6,6'-Bis(3,5-Dimethylphenyl)-2,2',3,3'-Tetrahydro-1,1'-Spirobi[1H-Indene]-7,7'-Diol
CAS No.	930784-56-8
Molecular Formula	C38H38O2
Molecular Weight	526.71 g/mol
Synonyms	(R)-6,6'-Bis(3,5-dimethylphenyl)-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol; (1R)-Spirobiindane-7,7'-diol Derivative; (R)-H8-BINOL Derivative; (R)-Octahydro-BINOL Derivative; (1R)-2,2',3,3'-Tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol, 6,6'-bis(3,5-dimethylphenyl)-; Ligand Precursor 930784-56-8; Chiral Spiro Diol
EINECS	Contact for details

Quality Control

Every batch of our (1R)- 6,6'-Bis(3,5-Dimethylphenyl)-2,2',3,3'-Tetrahydro-1,1'-Spirobi[1H-Indene]-7,7'-Diol is produced and controlled under a strict quality management system. We guarantee high chiral purity and chemical consistency through advanced analytical techniques including HPLC, chiral HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.