Description

(1R)-2,2',3,3'-Tetrahydro-6,6'-Diphenyl-1,1'-Spirobi[1H-Indene]-7,7'-Diol CAS NO 930784-55-7 is a high-purity, chiral spirobiindane derivative, a sophisticated organic intermediate prized for its rigid, three-dimensional structure. This compound matters as a critical building block for advanced materials and pharmaceuticals, enabling the synthesis of novel catalysts and ligands for asymmetric synthesis. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemistry and high-performance intermediates for complex molecular architectures.

Application

• Chiral Ligand Synthesis: A key precursor for developing novel phosphine, phosphoramidite, and N-heterocyclic carbene (NHC) ligands used in asymmetric catalysis.
• Pharmaceutical Intermediates: Serves as a core scaffold in the research and development of active pharmaceutical ingredients (APIs) requiring specific stereochemical configurations.
• Advanced Material Science: Used in the synthesis of organic semiconductors, liquid crystals, and polymers where a rigid, non-planar backbone is advantageous.
• Catalyst Development: Employed in the creation of homogeneous catalysts for hydrogenation, cross-coupling, and other enantioselective transformations.
• Agrochemical Research: Acts as an intermediate for novel, stereochemically-defined crop protection agents and plant growth regulators.
• Academic & Industrial R&D: A valuable tool for chemists exploring new reaction methodologies and constructing complex molecular frameworks.

Basic Information

Product Name	(1R)-2,2',3,3'-Tetrahydro-6,6'-Diphenyl-1,1'-Spirobi[1H-Indene]-7,7'-Diol
CAS No.	930784-55-7
Molecular Formula	C31H26O2
Molecular Weight	430.54 g/mol
Synonyms	(1R)-6,6'-Diphenyl-1,1'-spirobi[1H-indene]-7,7'-diol; (R)-6,6'-Diphenyl-1,1'-spirobiindane-7,7'-diol; (R)-SPINOL; (R)-6,6'-Bis(phenyl)-SPINOL; (1R)-2,2',3,3'-Tetrahydro-6,6'-diphenyl-1,1'-spirobi[1H-indene]-7,7'-diol; (R)-2,2',3,3'-Tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol, 6,6'-diphenyl-; (R)-VAPOL precursor; (1R)-7,7'-Dihydroxy-6,6'-diphenyl-1,1'-spirobiindane
EINECS	Contact for details

Quality Control

Our (1R)-2,2',3,3'-Tetrahydro-6,6'-Diphenyl-1,1'-Spirobi[1H-Indene]-7,7'-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.