Description

(1R)-2,2',3,3'-Tetrahydro-6,6'-Dimethyl-1,1'-Spirobi[1H-Indene]-7,7'-Diol is a high-purity, chiral spirobiindane derivative with significant utility in advanced organic synthesis. This compound serves as a critical chiral building block or ligand for the development of asymmetric catalysts and pharmaceuticals. It is primarily needed by research institutions and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Asymmetric Synthesis: As a chiral ligand or auxiliary in transition metal catalysis for enantioselective C-C and C-X bond formation.
• Pharmaceutical Intermediates: A key precursor in the synthesis of complex, optically active drug molecules targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Development: Used in the research and production of chiral pesticides and herbicides for enhanced efficacy and environmental profile.
• Material Science: Potential monomer or additive for creating chiral polymers and advanced organic electronic materials.
• Academic & Industrial R&D: A valuable tool compound for methodological development in organic chemistry and catalysis research.

Basic Information

Product Name	(1R)-2,2',3,3'-Tetrahydro-6,6'-Dimethyl-1,1'-Spirobi[1H-Indene]-7,7'-Diol
CAS No.	930784-54-6
Molecular Formula	C21H22O2
Molecular Weight	306.40 g/mol
Synonyms	(1R)-6,6'-Dimethyl-1,1'-spirobi[1H-indene]-7,7'-diol, 2,2',3,3'-tetrahydro-; (1R)-2,2',3,3'-Tetrahydro-6,6'-dimethyl-1,1'-spirobi[1H-indene]-7,7'-diol; (R)-6,6'-Dimethyl-1,1'-spirobi[indane]-7,7'-diol; (R)-Spirobiindane-7,7'-diol derivative; Chiral spirobiindanediol; (1R)-enantiomer of SKF-38393 core; (R)-Tetrahydromethylspirobiindanediol
EINECS	Contact for details

Quality Control

Our (1R)-2,2',3,3'-Tetrahydro-6,6'-Dimethyl-1,1'-Spirobi[1H-Indene]-7,7'-Diol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure compliance with research and fine chemical grade standards. Comprehensive Certificates of Analysis (COA) with full analytical data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) in a sealed container to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.