Description

(1R)- 2,2',3,3'-Tetrahydro-6,6'-Diiodo-7,7'-Bis(Methoxymethoxy)-1,1'-Spirobi[1H-Indene] is a sophisticated chiral spirobiindene derivative, a high-value synthetic intermediate prized for its complex molecular architecture. This compound is critical for enabling advanced research and development in asymmetric synthesis and materials science. It is primarily sought by pharmaceutical R&D teams and specialty chemical manufacturers for constructing novel molecular scaffolds and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research.
• Catalyst & Ligand Synthesis: Serves as a precursor for developing advanced chiral ligands and organocatalysts used in enantioselective transformations.
• Advanced Materials Research: Used in the development of chiral organic semiconductors and functional materials with specific optical or electronic properties.
• Asymmetric Synthesis: Employed in academic and industrial laboratories for constructing complex, stereodefined molecular architectures.
• Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in chemical manufacturing.

Basic Information

Product Name	(1R)- 2,2',3,3'-Tetrahydro-6,6'-Diiodo-7,7'-Bis(Methoxymethoxy)-1,1'-Spirobi[1H-Indene]
CAS No.	930784-50-2
Molecular Formula	C23H24I2O4
Molecular Weight	634.14 g/mol
Synonyms	(1R)-6,6'-Diiodo-7,7'-bis(methoxymethoxy)-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]; (R)-6,6'-Diiodo-7,7'-bis(methoxymethoxy)-2,2',3,3'-tetrahydro-1,1'-spirobiindene; (1R)-6,6'-Diiodo-7,7'-bis(MOM)-2,2',3,3'-tetrahydro-1,1'-spirobiindene; (R)-MOM-Protected Spirobiindene Iodide; (1R)-Tetrahydrosiprobiindene Derivative; 930784-50-2; (R)-enantiomer of the diiodo bis-MOM spirobiindene.
EINECS	Contact for details

Quality Control

Every batch of this high-purity intermediate is produced and tested under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity (typically ≥95% by HPLC), chiral purity (≥99% ee), and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability, consistency, and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged manipulations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.