Description

(1R)-2,2',3,3'-Tetrahydro-7,7'-Bis(Methoxymethoxy)-1,1'-Spirobi[1H-Indene] is a sophisticated chiral spirocyclic compound that serves as a critical intermediate in advanced organic synthesis. Its unique, rigid three-dimensional structure makes it a valuable building block for constructing complex molecules with precise stereochemistry. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Asymmetric Catalysis Ligand Precursor: Used to develop novel chiral ligands and catalysts for enantioselective synthesis.
• Advanced Material Science: Serves as a core structure for creating chiral organic frameworks, liquid crystals, or specialty polymers.
• Academic & R&D: A valuable tool for methodological development in organic chemistry and stereochemistry studies.
• Fine Chemical Synthesis: Intermediate for producing high-value, complex agrochemicals or fragrance molecules requiring specific chirality.

Basic Information

Product Name	(1R)-2,2',3,3'-Tetrahydro-7,7'-Bis(Methoxymethoxy)-1,1'-Spirobi[1H-Indene]
CAS No.	930784-49-9
Molecular Formula	C23H28O4
Molecular Weight	368.47 g/mol
Synonyms	(1R)-7,7'-Bis(methoxymethoxy)-1,1',2,2',3,3'-hexahydrospirobi[1H-indene]; (1R)-Bis-MOM-protected Spirobiindane; (R)-2,2',3,3'-Tetrahydro-7,7'-bis(methoxymethoxy)-1,1'-spirobi[1H-indene]; (1R)-Hexahydro-7,7'-bis(methoxymethoxy)spirobi[indene-1,1'-indene]; Spirobiindane derivative, MOM-protected; (R)-Spirobiindane bis-MOM ether; Chiral Spirocyclic Diol Protecting Group Intermediate
EINECS	Contact for details

Quality Control

Our production of (1R)-2,2',3,3'-Tetrahydro-7,7'-Bis(Methoxymethoxy)-1,1'-Spirobi[1H-Indene] adheres to stringent quality protocols suitable for R&D and cGMP manufacturing environments. Every batch is characterized using advanced analytical techniques to ensure identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing comprehensive specifications are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.