Description

3-Methylpyridine-2-Boronic Acid CAS NO 930303-26-7 is a high-purity organoboron compound, specifically a pyridine-substituted boronic acid, serving as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery, catalyst development, and functional material synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing functionalized bipyridine or terpyridine motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with complex heterocyclic cores for enhanced efficacy.
• Material Science: Building block for metal-organic frameworks (MOFs), organic light-emitting diodes (OLEDs), and conductive polymers.
• Catalyst Ligand Preparation: Serves as a starting material for synthesizing sophisticated nitrogen-boron chelating ligands used in homogeneous catalysis.
• Chemical Research & Development: Fundamental reagent in academic and industrial R&D for exploring new C-C bond-forming methodologies and library synthesis.
• Diagnostic Reagent Manufacturing: Potential use in developing fluorescent probes and sensor molecules due to its boronic acid functionality.

Basic Information

Product Name	3-Methylpyridine-2-Boronic Acid
CAS No.	930303-26-7
Molecular Formula	C6H8BNO2
Molecular Weight	136.95 g/mol
Synonyms	(3-Methylpyridin-2-yl)boronic acid; 2-Borono-3-methylpyridine; 3-Methyl-2-pyridineboronic acid; 3-Methylpyridine-2-boronic Acid Pinacol Ester (common precursor); 3-Methyl-2-pyridinylboronic acid; 2-(3-Methylpyridinyl)boronic acid; Boronic acid, B-(3-methyl-2-pyridinyl)-; 3-Methyl-2-boronopyridine
EINECS	Contact for details

Quality Control

Our 3-Methylpyridine-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.