Description

tert-Butyl 2-(3-Hydroxypropoxy)Acetate is a versatile bifunctional chemical intermediate containing both a protected carboxylic acid group and a primary hydroxyl group. This molecular structure makes it a valuable building block for the synthesis of more complex molecules, particularly in pharmaceutical and fine chemical applications. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), leveraging its reactive ester and alcohol functionalities for further derivatization.
• Prodrug Synthesis: Used in the design and development of prodrugs, where the tert-butyl ester group can serve as a protecting group or a cleavable moiety for controlled drug release.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers, coatings, and resins with tailored properties.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Useful precursor for synthesizing novel ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research & Development: A valuable tool for organic synthesis in academic and industrial R&D laboratories for exploring new chemical entities.

Basic Information

Product Name	tert-Butyl 2-(3-Hydroxypropoxy)Acetate
CAS No.	930294-38-5
Molecular Formula	C9H18O4
Molecular Weight	190.24 g/mol
Synonyms	2-(3-Hydroxypropoxy)acetic acid tert-butyl ester; Acetic acid, 2-(3-hydroxypropoxy)-, 1,1-dimethylethyl ester; tert-Butyl 2-(3-hydroxypropoxy)ethanoate; 1,1-Dimethylethyl 2-(3-hydroxypropoxy)acetate; TBHPA; Glycolic acid tert-butyl ester 3-hydroxypropyl ether
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(3-Hydroxypropoxy)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage under an inert atmosphere (nitrogen or argon), please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.