Description

4-Chloro-1,5-Naphthyridin-3-Amine is a high-purity, functionalized naphthyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated and aminated structure, which enables precise molecular modifications essential for developing novel compounds. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the naphthyridine scaffold into more complex molecular architectures.
• Academic & Industrial R&D: A valuable reagent for medicinal chemistry programs and exploratory research in heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-1,5-Naphthyridin-3-Amine
CAS No.	930276-73-6
Molecular Formula	C8H6ClN3
Molecular Weight	179.61 g/mol
Synonyms	3-Amino-4-chloro-1,5-naphthyridine; 4-Chloro-1,5-naphthyridin-3-amine; 4-Chloro-1,5-naphthyridine-3-amine; 1,5-Naphthyridine, 4-chloro-3-amino-; 930276-73-6; 4-Chloro-3-amino-1,5-naphthyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-1,5-Naphthyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.