Description

Pentafluorophenyl 1-(Thien-2-Ylmethyl)Piperidine-4-Carboxylate 97% is a high-purity, advanced pharmaceutical intermediate and building block. This compound is valued for its unique molecular architecture, combining a pentafluorophenyl ester with a substituted piperidine-thiophene moiety, which is critical for introducing specific physicochemical properties into target molecules. It is primarily required by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the creation of advanced active ingredients for crop protection products, leveraging its fluorine-containing group for enhanced bioactivity and environmental stability.
• Chemical Biology Probe Development: Serves as a precursor for synthesizing labeled compounds or affinity probes used in target identification and validation studies.
• Material Science Research: Employed in the synthesis of specialty polymers or organic electronic materials where the thiophene and fluorinated aromatic units can modulate electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	Pentafluorophenyl 1-(Thien-2-Ylmethyl)Piperidine-4-Carboxylate 97%
CAS No.	930111-06-1
Molecular Formula	C18H14F5NO2S
Molecular Weight	403.37 g/mol
Synonyms	1-[(Thiophen-2-yl)methyl]piperidine-4-carboxylic acid pentafluorophenyl ester; Pentafluorophenyl 1-[(thiophen-2-yl)methyl]piperidine-4-carboxylate; 1-(Thien-2-ylmethyl)piperidine-4-carboxylic acid pentafluorophenyl ester; 4-Carboxy-1-(2-thienylmethyl)piperidine pentafluorophenyl ester; PFP-1-(2-Thienylmethyl)piperidine-4-carboxylate
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl 1-(Thien-2-Ylmethyl)Piperidine-4-Carboxylate 97% is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity confirmation and NMR for structural verification, to ensure it meets the specified 97% minimum purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.