Description

trans-Tetrahydro-4-(Methylthio)-3-Furanamine is a specialized chiral amine building block featuring a tetrahydrofuran ring substituted with a methylthio group. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical sector where its unique stereochemistry and functional groups are valuable. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structure can contribute to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.
• Academic and R&D: A valuable reagent in university and corporate research laboratories for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	trans-Tetrahydro-4-(Methylthio)-3-Furanamine
CAS No.	930101-14-7
Molecular Formula	C6H13NOS
Molecular Weight	147.24 g/mol
Synonyms	trans-4-(Methylthio)-3-aminotetrahydrofuran; (3R,4S)-4-(Methylthio)tetrahydrofuran-3-amine; (3S,4R)-4-(Methylthio)tetrahydrofuran-3-amine; 3-Amino-4-(methylthio)tetrahydrofuran; 4-(Methylthio)-3-tetrahydrofuranamine; THF-amine methylthio derivative; Chiral furanamine building block
EINECS	Contact for details

Quality Control

Our trans-Tetrahydro-4-(Methylthio)-3-Furanamine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.