Description

n-Boc-7-Benzyl-2,7-Diazaspiro[3.5]Nonane is a high-value, protected spirocyclic diamine building block used in advanced organic synthesis. This compound is critical for medicinal chemistry research, enabling the construction of complex molecular architectures with precise stereochemical control. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs), particularly in the areas of central nervous system (CNS) and oncology therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting GPCRs and kinases.
• Medicinal Chemistry Scaffold: Used to introduce the constrained 2,7-diazaspiro[3.5]nonane moiety, which can improve potency and metabolic stability.
• Peptidomimetic Research: Serves as a rigid diamine component in the design of protease inhibitors and other bioactive peptides.
• Chemical Biology Probe Development: Employed in creating tool compounds for target identification and validation studies.
• Library Synthesis for HTS: A valuable building block for generating diverse compound libraries for high-throughput screening.
• Agrochemical Research: Potential intermediate in the development of novel herbicides or fungicides with new modes of action.

Basic Information

Product Name	n-Boc-7-Benzyl-2,7-Diazaspiro[3.5]Nonane
CAS No.	929301-99-5
Molecular Formula	C19H28N2O2
Molecular Weight	316.44 g/mol
Synonyms	tert-Butyl 7-benzyl-2,7-diazaspiro[3.5]nonane-2-carboxylate; 2,7-Diazaspiro[3.5]nonane-2-carboxylic acid, 7-(phenylmethyl)-, 1,1-dimethylethyl ester; 7-Benzyl-2-(tert-butoxycarbonyl)-2,7-diazaspiro[3.5]nonane; Boc-7-Bn-2,7-diazaspiro[3.5]nonane; 2-Boc-7-Benzyl-2,7-diazaspiro[3.5]nonane; 929301-99-5; 2,7-Diazaspiro[3.5]nonane, N-Boc-N'-benzyl-
EINECS	Contact for details

Quality Control

Our n-Boc-7-Benzyl-2,7-Diazaspiro[3.5]Nonane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.