Description

4-Ethyl-Piperidine-1,2-Dicarboxylic Acid 1-Benzyl Ester is a high-purity, synthetically valuable piperidine derivative. This compound serves as a critical chiral building block and advanced intermediate in the synthesis of complex pharmaceutical molecules and fine chemicals. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing nitrogen-containing heterocycles and developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of central nervous system (CNS) active drugs, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Building block for creating novel pesticides and herbicides with specific stereochemical configurations.
• Catalyst Ligand Precursor: Used in the preparation of chiral ligands for asymmetric catalysis and transition metal complexes.
• Fine Chemical Production: Intermediate in the synthesis of specialty chemicals, flavors, and fragrances requiring piperidine scaffolds.
• Academic & Contract Research: Essential material for medicinal chemistry research, process optimization, and route scouting in laboratory settings.
• Peptidomimetics Development: Used to introduce constrained, chiral diacid motifs into peptide analogs to enhance stability and bioavailability.

Basic Information

Product Name	4-Ethyl-Piperidine-1,2-Dicarboxylic Acid 1-Benzyl Ester
CAS No.	929195-54-0
Molecular Formula	C16H21NO4
Molecular Weight	291.34 g/mol
Synonyms	1-Benzyl 4-ethyl piperidine-1,2-dicarboxylate; 1-Benzyl 2-carboxy-4-ethylpiperidine-1-carboxylate; 4-Ethyl-1,2-piperidinedicarboxylic acid 1-benzyl ester; 4-Ethylpiperidine-1,2-dicarboxylic acid benzyl ester; 4-Ethyl-2-piperidinecarboxylic acid, 1-(benzyloxycarbonyl)-; (2S,4S)-4-Ethyl-1-[(benzyloxy)carbonyl]piperidine-2-carboxylic acid (for stereoisomers); 929195-54-0; Z-4-Et-Pip(1,2)-OH (abbrev.)
EINECS	Contact for details

Quality Control

Our 4-Ethyl-Piperidine-1,2-Dicarboxylic Acid 1-Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the stringent requirements for advanced pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic confirmation (NMR, IR) are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (specify isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.