Description

(S)-Methyl 2-Hydroxy-3-(4-Nitrophenyl)Propanoate CAS NO 929083-97-6 is a high-purity chiral intermediate featuring a nitroaromatic group and a β-hydroxy ester moiety. This compound is valued for its role as a critical building block in the synthesis of complex, optically active pharmaceuticals and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of β-blockers, enzyme inhibitors, and other active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Research: Used in the development of novel herbicides and pesticides where the (S)-enantiomer provides targeted biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce the 2-hydroxy-3-(4-nitrophenyl)propanoate fragment into more complex molecular architectures.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological studies in stereoselective synthesis and medicinal chemistry.

Basic Information

Product Name	(S)-Methyl 2-Hydroxy-3-(4-Nitrophenyl)Propanoate
CAS No.	929083-97-6
Molecular Formula	C10H11NO5
Molecular Weight	225.20 g/mol
Synonyms	(S)-Methyl 2-Hydroxy-3-(4-nitrophenyl)propionate; Methyl (2S)-2-hydroxy-3-(4-nitrophenyl)propanoate; (S)-2-Hydroxy-3-(4-nitrophenyl)propionic acid methyl ester; (S)-Methyl 3-(4-nitrophenyl)-2-hydroxypropanoate; (S)-Methyl 3-(p-nitrophenyl)-2-hydroxypropionate; (S)-Methyl β-hydroxy-p-nitrophenylpropionate; (S)-Methyl OND
EINECS	Contact for details

Quality Control

Our (S)-Methyl 2-Hydroxy-3-(4-Nitrophenyl)Propanoate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.