Description

3-Pyridinamine, 6-Chloro-4-(4-Fluoro-2-Methylphenyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated pyridine structure. This compound is of significant commercial importance for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Serves as a foundational scaffold for developing new-generation pesticides and herbicides, leveraging its halogenated aromatic system.
• Chemical Synthesis: Used in organic synthesis for constructing complex heterocyclic compounds and for introducing specific functional groups in medicinal chemistry.
• Material Science Research: Potential application as a monomer or ligand in the development of specialized polymers and coordination complexes.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	3-Pyridinamine, 6-Chloro-4-(4-Fluoro-2-Methylphenyl)-
CAS No.	929048-28-2
Molecular Formula	C12H10ClFN2
Molecular Weight	236.67 g/mol
Synonyms	6-Chloro-4-(4-fluoro-2-methylphenyl)pyridin-3-amine; 6-Chloro-4-(4-fluoro-2-methylphenyl)-3-pyridinamine; 4-(4-Fluoro-2-methylphenyl)-6-chloropyridin-3-amine; 929048-28-2; 6-Chloro-4-(4-fluoro-o-tolyl)pyridin-3-amine; 3-Amino-6-chloro-4-(4-fluoro-2-methylphenyl)pyridine
EINECS	Contact for details

Quality Control

Our 3-Pyridinamine, 6-Chloro-4-(4-Fluoro-2-Methylphenyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.