Description

2-Chloro-4-Fluoronicotinic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique halogenated structure makes it an indispensable intermediate for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and pesticides with enhanced efficacy and selectivity.
• Ligand & Catalyst Development: Employed in the creation of novel ligands and organocatalysts for asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Acts as a precursor for fluorinated organic electronic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	2-Chloro-4-Fluoronicotinic Acid
CAS No.	929022-76-4
Molecular Formula	C6H3ClFNO2
Molecular Weight	175.55 g/mol
Synonyms	2-Chloro-4-fluoropyridine-3-carboxylic acid; 3-Carboxy-2-chloro-4-fluoropyridine; 4-Fluoro-2-chloronicotinic acid; 2-Chloro-4-fluoro-3-pyridinecarboxylic acid; 929022-76-4; Nicotinic acid, 2-chloro-4-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoronicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high purity for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its acidic nature, handle with appropriate personal protective equipment in a controlled environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.