Description

Methyl 5-Bromo-2-Methylthiobenzoate is a high-purity organic building block and key synthetic intermediate of significant commercial importance. Its unique structure, featuring both bromo and methylthio substituents, makes it a versatile precursor for constructing complex molecules in advanced research and development. This compound is primarily utilized by pharmaceutical, agrochemical, and material science industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a key precursor for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and advanced polymers due to its electron-rich aromatic system.
• Chemical Biology & Proteomics: Employed as a reagent for protein labeling and the development of molecular probes to study biological pathways.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	Methyl 5-Bromo-2-Methylthiobenzoate
CAS No.	929000-14-6
Molecular Formula	C9H9BrO2S
Molecular Weight	261.14 g/mol
Synonyms	5-Bromo-2-(methylthio)benzoic acid methyl ester; Methyl 5-bromo-2-(methylthio)benzoate; Benzoic acid, 5-bromo-2-(methylthio)-, methyl ester; 2-Methylthio-5-bromobenzoic acid methyl ester; 929000-14-6; Methyl 5-bromo-2-methylsulfanylbenzoate
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-2-Methylthiobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.