Description

2,4,5,6,7,8-Hexahydro-Pyrazolo[3,4-D]Azepine, Hydrochloride is a high-purity, nitrogen-containing heterocyclic building block and pharmaceutical intermediate. This compound is valued for its rigid, fused bicyclic structure, which is critical for imparting specific biological activity and molecular recognition properties in advanced drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a privileged scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes to study enzyme function and biological pathways.
• Organic Synthesis Building Block: Employed in complex multi-step organic syntheses due to its reactive functional groups and constrained geometry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	2,4,5,6,7,8-Hexahydro-Pyrazolo[3,4-D]Azepine, Hydrochloride
CAS No.	928774-98-5
Molecular Formula	C8H14ClN3
Molecular Weight	187.67 g/mol
Synonyms	Pyrazolo[3,4-d]azepine, 2,4,5,6,7,8-hexahydro-, hydrochloride; 2,4,5,6,7,8-Hexahydro-1H-pyrazolo[3,4-d]azepine hydrochloride; 1H-Pyrazolo[3,4-d]azepine, 2,4,5,6,7,8-hexahydro-, hydrochloride; 928774-98-5; Hexahydropyrazolo[3,4-d]azepine HCl; Pyrazoloazepine hydrochloride derivative
EINECS	Contact for details

Quality Control

Our 2,4,5,6,7,8-Hexahydro-Pyrazolo[3,4-D]Azepine, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.