Description

5-Bromo-3-Iodo-Pyrrolo[2,3-B]Pyridine-1-Carboxylicacidtert-Butylester is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists working on kinase inhibitors, targeted cancer therapies, and other small-molecule drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery campaigns.
• Chemical Biology: Serves as a versatile probe or linker for developing chemical tools and bioconjugates.
• Agrochemical Research: Potential building block for developing new active ingredients with specific biological activity.
• Material Science: Can be utilized in the synthesis of organic electronic materials and advanced polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	5-Bromo-3-Iodo-Pyrrolo[2,3-B]Pyridine-1-Carboxylicacidtert-Butylester
CAS No.	928653-81-0
Molecular Formula	C12H12BrIN2O2
Molecular Weight	423.05 g/mol
Synonyms	1-(tert-Butyl) 5-Bromo-3-Iodo-1H-Pyrrolo[2,3-b]pyridine-1-carboxylate; tert-Butyl 5-Bromo-3-Iodo-1H-Pyrrolo[2,3-b]pyridine-1-carboxylate; 5-Bromo-3-iodo-1H-pyrrolo[2,3-b]pyridine-1-carboxylic Acid tert-Butyl Ester; 5-Br-3-I-7-Azaindole-1-COOtBu; 5-Bromo-3-iodo-7-azaindole-1-carboxylic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Iodo-Pyrrolo[2,3-B]Pyridine-1-Carboxylicacidtert-Butylester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ICH guidelines ensure the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.