Description

5-Chloro-3-Iodo-Pyrrolo[2,3-B]Pyridine-1-Carboxylicacidtert-Butylester is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel pharmaceutical agents, particularly in kinase inhibitor research and other targeted therapeutic areas. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to construct complex molecular architectures.

Application

• Key synthetic intermediate in the research and development of novel kinase inhibitors for oncology and other therapeutic areas.
• Building block for constructing complex pyrrolopyridine-based scaffolds in medicinal chemistry programs.
• Precursor in the synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemicals.
• Used in cross-coupling reactions (e.g., Suzuki, Sonogashira) facilitated by the reactive iodine substituent.
• Intermediate for creating functionalized heterocycles for material science and chemical biology applications.
• Starting material for the preparation of custom ligands and organocatalysts.

Basic Information

Product Name	5-Chloro-3-Iodo-Pyrrolo[2,3-B]Pyridine-1-Carboxylicacidtert-Butylester
CAS No.	928653-79-6
Molecular Formula	C12H12ClIN2O2
Molecular Weight	378.59 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-5-chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 5-chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine-1-carboxylate; 5-Chloro-3-iodo-1-Boc-pyrrolo[2,3-b]pyridine; 5-Chloro-3-iodo-pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester; 928653-79-6
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Iodo-Pyrrolo[2,3-B]Pyridine-1-Carboxylicacidtert-Butylester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.