Description

5-Fluoro-3-Iodo-Pyrrolo[2,3-B]Pyridine-1-Carboxylicacidtert-Butylester is a high-value, multi-functional heterocyclic building block designed for advanced pharmaceutical and agrochemical research. This compound is critical for medicinal chemists seeking to introduce both fluorine and iodine atoms into complex molecular architectures, enabling precise modulation of biological activity and physicochemical properties. It is primarily utilized in the synthesis of targeted kinase inhibitors and other bioactive molecules within the pharmaceutical and life science sectors.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and lead optimization due to its versatile halogenated pyrrolopyridine core.
• Agrochemical Research: Serves as a building block for developing new active ingredients with enhanced efficacy and selectivity.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways and target engagement.
• Material Science: Potential precursor for advanced organic electronic materials and ligands in catalytic systems.

Basic Information

Product Name	5-Fluoro-3-Iodo-Pyrrolo[2,3-B]Pyridine-1-Carboxylicacidtert-Butylester
CAS No.	928653-78-5
Molecular Formula	C12H12FINO2
Molecular Weight	348.14 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-5-fluoro-3-iodo-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-3-iodo-1H-pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 5-fluoro-3-iodo-1H-pyrrolo[2,3-b]pyridine-1-carboxylate; 5-Fluoro-3-iodo-1-Boc-pyrrolo[2,3-b]pyridine; 928653-78-5; 5-Fluoro-3-iodo-1H-pyrrolo[2,3-b]pyridine-1-carboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of 5-Fluoro-3-Iodo-Pyrrolo[2,3-B]Pyridine-1-Carboxylicacidtert-Butylester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.