Description

3-Iodo-4-Methoxy-1H-Pyrrolo[2,3-B]Pyridine is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and the development of novel therapeutic agents, particularly kinase inhibitors. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of targeted small molecule drugs, especially kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to develop new chemical entities.
• Process Chemistry Development: Serves as a critical starting material or intermediate in the scale-up and route development for Active Pharmaceutical Ingredient (API) manufacturing.
• Chemical Biology Probes: Can be utilized to create labeled compounds for studying biological pathways and target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery pipelines.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-Iodo-4-Methoxy-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	928653-75-2
Molecular Formula	C8H7IN2O
Molecular Weight	274.06 g/mol
Synonyms	4-Methoxy-3-iodo-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-4-methoxy-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 3-iodo-4-methoxy-; 928653-75-2; 4-Methoxy-3-iodo-7-azaindole; 3-Iodo-4-methoxy-7-azaindole; 7-Azaindole, 3-iodo-4-methoxy-
EINECS	Contact for details

Quality Control

Our 3-Iodo-4-Methoxy-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.