Description

1-(2-Chloro-5-(2-Fluorophenyl)-1-(Pyridin-3-Ylsulfonyl)-1H-Pyrrol-3-Yl)-n-Methylmethanamine is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure incorporating pyrrole, pyridine, and fluorophenyl moieties. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. Research and development teams in the global pharmaceutical and biotechnology sectors need this precise chemical to accelerate drug discovery programs and process development for new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry Research: Used by R&D laboratories for structure-activity relationship (SAR) studies and lead optimization due to its unique fused-ring system.
• API Process Development: Employed in scaling up and optimizing synthetic routes for new active pharmaceutical ingredients under Good Manufacturing Practice (GMP) guidelines.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for the production of clinical trial materials and commercial API batches.
• Biochemical Tool Compound: May be utilized in biochemical assays and as a probe to study specific biological pathways and enzyme interactions.
• Academic Research: Used in university and institutional labs for advanced organic synthesis projects and the development of new catalytic methodologies.

Basic Information

Product Name	1-(2-Chloro-5-(2-Fluorophenyl)-1-(Pyridin-3-Ylsulfonyl)-1H-Pyrrol-3-Yl)-n-Methylmethanamine
CAS No.	928325-68-2
Molecular Formula	C₁₇H₁₅ClFN₃O₂S
Molecular Weight	379.83 g/mol
Synonyms	N-Methyl-1-[2-chloro-5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]methanamine; 1-(2-Chloro-5-(2-fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine; 928325-68-2; UNII-9V6C6687FJ; 9V6C6687FJ; Methanamine, 1-[2-chloro-5-(2-fluorophenyl)-1-(3-pyridinylsulfonyl)-1H-pyrrol-3-yl]-N-methyl-; SCHEMBL21806227; ZINC000006926947
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and purity suitable for pharmaceutical research. Quality is verified through modern analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development under quality agreements and can align with GMP standards for projects requiring regulatory filing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.