Description

4-(2-(tert-Butyldimethylsilyloxy)Ethyl)-1-Trityl-1H-Imidazole is a sophisticated, multi-protected imidazole derivative of significant value in advanced organic synthesis. This compound matters as a critical, high-purity building block for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key protected precursor in the synthesis of novel drug candidates, particularly those containing imidazole or histidine-like pharmacophores.
• Peptidomimetic Synthesis: Used in the construction of complex peptidomimetics and macrocyclic compounds where the protected functional groups allow for selective deprotection and further coupling.
• Agrochemical Research: Acts as a building block for developing new fungicides, herbicides, or plant growth regulators that utilize heterocyclic chemistry.
• Ligand and Catalyst Development: Employed in the preparation of specialized N-heterocyclic ligands for metal catalysis or organocatalysts.
• Chemical Biology Probes: Useful for synthesizing tagged or modified biomolecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex, high-value specialty chemicals for clients.

Basic Information

Item	Details
Product Name	4-(2-(tert-Butyldimethylsilyloxy)Ethyl)-1-Trityl-1H-Imidazole
CAS No.	928136-82-7
Molecular Formula	C30H38N2OSi
Molecular Weight	470.73 g/mol
Synonyms	1-Trityl-4-[2-[(1,1-dimethylethyl)dimethylsilyl]oxyethyl]-1H-imidazole; 4-(2-((tert-Butyldimethylsilyl)oxy)ethyl)-1-trityl-1H-imidazole; 1H-Imidazole, 4-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-1-(triphenylmethyl)-; TBDMS-OEt-1-Trityl-imidazole; 4-(2-Hydroxyethyl)-1-trityl-1H-imidazole TBDMS ether
EINECS	Contact for details

Quality Control

Our 4-(2-(tert-Butyldimethylsilyloxy)Ethyl)-1-Trityl-1H-Imidazole is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. All batches are fully characterized by NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may benefit from storage under an inert atmosphere or with desiccant to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.