Description

1,8-Diazaspiro[4.5]Decane-8-Carboxylic Acid, Phenylmethyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and diaza structural motif. This compound is valued for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including potential candidates for neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Protease Inhibitor Development: Used in the research and synthesis of molecules targeting specific protease enzymes.
• Ligand Synthesis for Drug Discovery: Employed in creating sophisticated ligands for receptor binding studies and targeted therapies.
• Chemical Biology Probes: Utilized in the development of tool compounds for investigating biological pathways and mechanisms.
• Academic & Industrial R&D: Fundamental building block for exploratory synthetic chemistry in both academic and industrial settings.

Basic Information

Product Name	1,8-Diazaspiro[4.5]Decane-8-Carboxylic Acid, Phenylmethyl Ester
CAS No.	928114-04-9
Molecular Formula	C16H20N2O2
Molecular Weight	272.34 g/mol
Synonyms	Benzyl 1,8-diazaspiro[4.5]decane-8-carboxylate; 8-(Benzyloxycarbonyl)-1,8-diazaspiro[4.5]decane; 1,8-Diazaspiro[4.5]decane-8-carboxylic acid benzyl ester; Cbz-1,8-Diazaspiro[4.5]decane; 8-Cbz-1,8-Diazaspiro[4.5]decane; 1,8-Diazaspiro[4.5]decane-8-carboxylate benzyl ester; Benzyl 8-aza-1-azoniaspiro[4.5]decane-8-carboxylate (inner salt form); Z-1,8-Diazaspiro[4.5]decane
EINECS	Contact for details

Quality Control

Our 1,8-Diazaspiro[4.5]Decane-8-Carboxylic Acid, Phenylmethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for GMP-grade intermediates used in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.