Description

3-Bromo-2-Formylphenylboronic Acid is a versatile bifunctional aromatic building block that combines a formyl group and a boronic acid moiety on a brominated benzene ring. This unique structure makes it a critical intermediate for the synthesis of complex molecules via sequential cross-coupling and condensation reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex aromatic scaffolds.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for biochemical and pharmacological studies.
• Catalyst Ligand Development: Useful for constructing sophisticated ligand frameworks in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	3-Bromo-2-Formylphenylboronic Acid
CAS No.	928048-12-8
Molecular Formula	C7H6BBrO3
Molecular Weight	228.84 g/mol
Synonyms	(3-Bromo-2-formylphenyl)boronic acid; 2-Formyl-3-bromophenylboronic acid; 3-Bromo-2-formylbenzeneboronic acid; Boronic acid, B-(3-bromo-2-formylphenyl)-; 928048-12-8; 3-Bromo-2-carboxybenzaldehyde boronic acid (common name)
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Formylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.