Description

1,8-Diazaspiro[4.5]decane-1,8-dicarboxylic acid, 1-(1,1-dimethylethyl) 8-(phenylmethyl) ester is a high-value, protected spirocyclic diamine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in providing a rigid, three-dimensional scaffold that is essential for constructing complex molecular architectures with precise stereochemistry. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, including the development of novel active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry Scaffold: Used to create spirocyclic compound libraries for high-throughput screening (HTS) to identify new bioactive molecules.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and asymmetric synthesis.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides with unique modes of action.
• Peptidomimetics: Utilized to introduce conformational constraints in peptide analogs, enhancing their stability and biological activity.
• Academic & Contract Research: A valuable reagent for methodological development and complex natural product synthesis in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	1,8-Diazaspiro[4.5]decane-1,8-dicarboxylic acid, 1-(1,1-dimethylethyl) 8-(phenylmethyl) ester
CAS No.	928034-34-8
Molecular Formula	C21H30N2O4
Molecular Weight	374.48 g/mol
Synonyms	tert-Butyl benzyl 1,8-diazaspiro[4.5]decane-1,8-dicarboxylate; 1,8-Diazaspiro[4.5]decane-1,8-dicarboxylic acid 1-tert-butyl 8-benzyl ester; 1-(tert-Butoxycarbonyl)-8-(benzyloxycarbonyl)-1,8-diazaspiro[4.5]decane; Boc-Cbz-1,8-Diazaspiro[4.5]decane; 1,8-Bis(tert-butoxycarbonyl)-1,8-diazaspiro[4.5]decane derivative (protected form); Spirocyclic Diamine Ester; CAS 928034-34-8
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical synthesis work. Each lot is characterized by comprehensive analytical techniques including HPLC, NMR, and MS to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, chiral purity (if applicable), and impurity profiles. We operate under a quality management system and can support development projects requiring compliance with cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a dry, inert atmosphere to maximize shelf life and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.