Description

2-Hydroxy-5-Iodo-6-Methylpyridine is a halogenated pyridine derivative that serves as a versatile and high-value synthetic building block in advanced organic chemistry. Its unique structure, featuring both a hydroxyl and an iodine substituent, makes it a critical intermediate for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists engaged in the synthesis of novel active ingredients, where precise functionalization is required.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that require halogenated heterocyclic cores.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs) due to its potential for coordination and functionalization.
• Chemical Biology Probes: Utilized to synthesize molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-Hydroxy-5-Iodo-6-Methylpyridine
CAS No.	927870-76-6
Molecular Formula	C6H6INO
Molecular Weight	235.03 g/mol
Synonyms	5-Iodo-6-methylpyridin-2-ol; 6-Methyl-5-iodopyridin-2-ol; 5-Iodo-2-hydroxy-6-methylpyridine; 2-Hydroxy-5-iodo-6-picoline; 5-Iodo-6-methyl-2-pyridinol; 2-Pyridinol, 5-iodo-6-methyl-; 6-Methyl-5-iodo-2-pyridone (tautomer)
EINECS	Contact for details

Quality Control

Every batch of 2-Hydroxy-5-Iodo-6-Methylpyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.