Description

4-Thien-2-Yltetrahydro-2H-Pyran-4-Yl Isocyanate is a specialized heterocyclic isocyanate building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a reactive isocyanate group with a tetrahydro-2H-pyran ring and a thiophene moiety, enabling the creation of novel polymers and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities. Its precise structure offers a pathway to introduce specific steric and electronic properties into target molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research targeting CNS and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the heterocyclic components can contribute to biological activity.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, such as polyurethanes and polyureas, with tailored thermal or mechanical properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs as a versatile reagent for constructing complex heterocyclic scaffolds and exploring new chemical spaces.
• Ligand & Catalyst Development: The sulfur and oxygen heteroatoms make it a candidate for designing novel ligands for metal catalysis in asymmetric synthesis.

Basic Information

Item	Details
Product Name	4-Thien-2-Yltetrahydro-2H-Pyran-4-Yl Isocyanate
CAS No.	926921-63-3
Molecular Formula	C10H11NO2S
Molecular Weight	209.26 g/mol
Synonyms	4-(Thiophen-2-yl)tetrahydro-2H-pyran-4-yl isocyanate; 4-(2-Thienyl)tetrahydro-2H-pyran-4-yl isocyanate; 2H-Pyran-4-isocyanate, 4-(2-thienyl)tetrahydro-; Tetrahydro-4-(2-thienyl)-2H-pyran-4-yl isocyanate; 4-(Thiophen-2-yl)oxan-4-yl isocyanate; Isocyanic acid, 4-(2-thienyl)tetrahydro-2H-pyran-4-yl ester
EINECS	Contact for details

Quality Control

Our 4-Thien-2-Yltetrahydro-2H-Pyran-4-Yl Isocyanate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.