Description

1-Methyl-5-[4-(Trifluoromethyl)Phenyl]-3-Azabicyclo[3.1.0]Hexane is a high-value, structurally complex bicyclic amine derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. Its unique fused-ring scaffold and trifluoromethylphenyl moiety make it indispensable for the research and development of novel bioactive compounds. This compound is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, antiviral agents, and other therapeutic areas.
• Agrochemical Research: Used as a core scaffold for developing novel pesticides and herbicides, leveraging the biological activity of the trifluoromethyl group.
• Ligand & Catalyst Development: Serves as a sophisticated ligand in asymmetric catalysis and organometallic chemistry for creating chiral compounds.
• Material Science: Investigated as a monomer or additive for specialty polymers with unique thermal or optical properties.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, multi-cyclic amine frameworks.

Basic Information

Product Name	1-Methyl-5-[4-(Trifluoromethyl)Phenyl]-3-Azabicyclo[3.1.0]Hexane
CAS No.	926907-00-8
Molecular Formula	C14H14F3N
Molecular Weight	253.26 g/mol
Synonyms	1-Methyl-5-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane; 3-Azabicyclo[3.1.0]hexane, 1-methyl-5-[4-(trifluoromethyl)phenyl]-; Bicyclo[3.1.0]hexane, 1-methyl-5-(4-(trifluoromethyl)phenyl)-3-aza-; 1-Methyl-5-(4-trifluoromethylphenyl)-3-azabicyclo[3.1.0]hexane; 926907-00-8; 3-Azabicyclo[3.1.0]hexane derivative; Trifluoromethylphenyl azabicyclohexane.
EINECS	Contact for details

Quality Control

Our production of 1-Methyl-5-[4-(Trifluoromethyl)Phenyl]-3-Azabicyclo[3.1.0]Hexane adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and structural integrity. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.