Description

tert-Butyl 3-(pyridin-4-yloxy)azetidine-1-carboxylate is a high-purity, protected azetidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex nitrogen-containing heterocycles, which are core scaffolds in modern pharmaceuticals. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. The product, CAS 926906-38-9, is supplied to meet the stringent requirements of process chemistry and medicinal chemistry applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of small molecule drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to introduce the azetidine-pyridyl ether pharmacophore.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides, fungicides, or insecticides that utilize nitrogen heterocycles for bioactivity.
• Chemical Biology Probes: Serves as a precursor for creating tool compounds and probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.
• Academic Research: Used in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 3-(Pyridin-4-yloxy)azetidine-1-carboxylate
CAS No.	926906-38-9
Molecular Formula	C13H18N2O3
Molecular Weight	250.30 g/mol
Synonyms	1-Boc-3-(4-pyridyloxy)azetidine; 1-(tert-Butoxycarbonyl)-3-(4-pyridinyloxy)azetidine; tert-Butyl 3-[(pyridin-4-yl)oxy]azetidine-1-carboxylate; 3-(Pyridin-4-yloxy)azetidine-1-carboxylic acid tert-butyl ester; 1-N-Boc-3-(4-pyridyloxy)azetidine; Azetidine-1-carboxylic acid, 3-(4-pyridinyloxy)-, 1,1-dimethylethyl ester; 926906-38-9
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(pyridin-4-yloxy)azetidine-1-carboxylate is manufactured under strict quality control protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality system is designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical development, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.