Description

Racemic-(1R,2R)-2'-Oxospiro[Cyclopropane-1,3'-Indoline]-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic indoline scaffold. This compound is valued for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought after by pharmaceutical companies and contract research organizations (CROs) focused on developing novel therapeutics, including potential central nervous system (CNS) agents and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery programs targeting various disease pathways.
• Synthesis of Biologically Active Compounds: Used in the preparation of potential therapeutic agents, including protease inhibitors and receptor modulators.
• Asymmetric Synthesis: The racemic mixture can be utilized in chiral resolution studies or as a starting material for the preparation of enantiomerically pure derivatives.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and biological mechanisms.

Basic Information

Product Name	Racemic-(1R,2R)-2'-Oxospiro[Cyclopropane-1,3'-Indoline]-2-Carboxylic Acid
CAS No.	926667-78-9
Molecular Formula	C12H11NO3
Molecular Weight	217.22 g/mol
Synonyms	(±)-(1R,2R)-2'-Oxospiro[cyclopropane-1,3'-indoline]-2-carboxylic acid; 2'-Oxospiro[cyclopropane-1,3'-indoline]-2-carboxylic acid, (1R,2R)-, (±)-; rac-(1R,2R)-2'-Oxospiro[cyclopropane-1,3'-indoline]-2-carboxylic acid; Spiro[cyclopropane-1,3'-indoline]-2-carboxylic acid, 2'-oxo-, (±)-, (1R,2R)-; 926667-78-9; (1R,2R)-rel-2'-Oxospiro[cyclopropane-1,3'-indoline]-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our Racemic-(1R,2R)-2'-Oxospiro[Cyclopropane-1,3'-Indoline]-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with the standards required for pharmaceutical R&D and cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.