Description

1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid, 6-(4-Fluorophenyl)-3-Methyl-, Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical companies and contract research organizations (CROs) focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Kinase Inhibitor Development: Serves as a core scaffold for research into protein kinase inhibitors, a major class of therapeutics for cancer and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Custom Synthesis: Employed by fine chemical manufacturers for the contract synthesis of complex molecules for preclinical and clinical trials.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid, 6-(4-Fluorophenyl)-3-Methyl-, Ethyl Ester
CAS No.	926282-91-9
Molecular Formula	C₁₈H₁₆FN₃O₂
Molecular Weight	325.34 g/mol
Synonyms	Ethyl 6-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate; 6-(4-Fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid ethyl ester; 926282-91-9; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 6-(4-fluorophenyl)-3-methyl-, ethyl ester; Ethyl 6-(p-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid, 6-(4-Fluorophenyl)-3-Methyl-, Ethyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.