Description

n-(5-Amino-2-Fluorophenyl)Nicotinamide is a high-purity, fluorinated aromatic amide building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents and agrochemicals, where its unique molecular scaffold enables the creation of targeted bioactive molecules. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and receptor antagonist research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its fluorinated aromatic structure.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study biological pathways and protein functions.
• Material Science Research: Investigated as a monomer or additive for the development of advanced polymers with specific optical or electronic properties.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for client projects.

Basic Information

Product Name	n-(5-Amino-2-Fluorophenyl)Nicotinamide
CAS No.	926241-83-0
Molecular Formula	C12H10FN3O
Molecular Weight	231.23 g/mol
Synonyms	5-Amino-2-fluoro-N-(pyridin-3-yl)benzamide; Nicotinamide, N-(5-amino-2-fluorophenyl)-; 3-Pyridinecarboxamide, N-(5-amino-2-fluorophenyl)-; N-(5-Amino-2-fluorophenyl)pyridine-3-carboxamide; 926241-83-0; AKOS005258065; FT-0773935
EINECS	Contact for details

Quality Control

Our n-(5-Amino-2-Fluorophenyl)Nicotinamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening a new container to maintain purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.