Description

1H-Pyrrolo[2,3-B]Pyridine-4-Carboxaldehyde, 5-Methoxy-1-[Tris(1-Methylethyl)Silyl]- is a high-value, protected heterocyclic aldehyde building block used in advanced organic synthesis. This compound is critical for the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection products.
• Material Science Precursor: Serves as a starting material for creating functionalized organic semiconductors or ligands for catalytic systems.
• Academic & Contract Research: Essential for medicinal chemistry programs and methodology development in university and CRO laboratories.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-4-Carboxaldehyde, 5-Methoxy-1-[Tris(1-Methylethyl)Silyl]-
CAS No.	926004-76-4
Molecular Formula	C18H28N2O2Si
Molecular Weight	332.52 g/mol
Synonyms	5-Methoxy-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-4-carboxaldehyde; 5-Methoxy-1-triisopropylsilyl-1H-pyrrolo[2,3-b]pyridine-4-carbaldehyde; 1-Triisopropylsilyl-5-methoxy-1H-pyrrolo[2,3-b]pyridine-4-carboxaldehyde; 5-Methoxy-1-(triisopropylsilyl)-4-formyl-7-azaindole; TIPS-Protected 5-Methoxy-7-azaindole-4-carboxaldehyde; 926004-76-4
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area. Due to its light-sensitive nature, handling should be performed under subdued lighting or using amber glass containers where practical.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.