Description

1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-5-Methoxy-1-[Tris(1-Methylethyl)Silyl]- is a high-value, organosilicon-protected heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key synthetic intermediate, enabling the precise construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its functionalized pyrrolopyridine core.
• Material Science: Acts as a building block for creating organic electronic materials and functional polymers due to its conjugated system and silyl protecting group.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: A key starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.
• Academic Research: Utilized in university and institutional labs for methodological development in heterocyclic and organosilicon chemistry.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-5-Methoxy-1-[Tris(1-Methylethyl)Silyl]-
CAS No.	926004-73-1
Molecular Formula	C17H27ClN2OSi
Molecular Weight	338.95 g/mol
Synonyms	4-Chloro-5-methoxy-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine; 1-(Triisopropylsilyl)-4-chloro-5-methoxypyrrolo[2,3-b]pyridine; 4-Chloro-5-methoxy-1-triisopropylsilyl-1H-pyrrolo[2,3-b]pyridine; TIPS-4-Chloro-5-methoxypyrrolo[2,3-b]pyridine; 1-TIPS-4-Chloro-5-methoxy-7-azaindole; 4-Chloro-5-methoxy-1H-pyrrolo[2,3-b]pyridine, 1-(triisopropylsilyl) derivative; 926004-73-1; 1-Triisopropylsilyl-4-chloro-5-methoxy-7-azaindole
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-5-Methoxy-1-[Tris(1-Methylethyl)Silyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to minimize degradation. This material is sensitive to fluoride/strong alkali; store separately from such reagents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.