Description

trans-tert-Butyl 3-Phenylaziridine-2-Carboxylate is a high-value, chiral aziridine derivative that serves as a critical building block in advanced organic synthesis. Its rigid, three-membered heterocyclic ring structure makes it an indispensable precursor for constructing complex nitrogen-containing molecules with high stereochemical control. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, chiral ligands, and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel APIs, particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced, stereospecific pesticides and herbicides.
• Chiral Ligand & Catalyst Preparation: Serves as a precursor for synthesizing sophisticated ligands used in asymmetric catalysis.
• Peptidomimetics & Constrained Analogs: Employed to introduce conformational rigidity into peptide backbones for structure-activity relationship (SAR) studies.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and material science research.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	trans-tert-Butyl 3-Phenylaziridine-2-Carboxylate
CAS No.	925253-03-8
Molecular Formula	C₁₃H₁₇NO₂
Molecular Weight	219.28 g/mol
Synonyms	trans-1-(tert-Butoxycarbonyl)-2-phenylaziridine; (2R,3S)-tert-Butyl 3-phenylaziridine-2-carboxylate; (2S,3R)-tert-Butyl 3-phenylaziridine-2-carboxylate; tert-Butyl trans-2-phenylaziridine-1-carboxylate; trans-2-Phenyl-N-Boc-aziridine; Aziridine-2-carboxylic acid, 3-phenyl-, 1,1-dimethylethyl ester, trans-; 1-Boc-2-phenylaziridine (trans); Phenylaziridine tert-butyl carboxylate
EINECS	Contact for details

Quality Control

Our trans-tert-Butyl 3-Phenylaziridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be sensitive to moisture and prolonged exposure to air; for long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.