Description

n-Hydroxysuccinimide 2-(Dodecylthiocarbonothioylthio)Isobutyrate is a specialized RAFT (Reversible Addition-Fragmentation Chain Transfer) agent, also known as a chain transfer agent, designed for controlled radical polymerization. This compound matters because it enables the precise synthesis of polymers with predetermined molecular weights, narrow molecular weight distributions, and specific end-group functionality. It is essential for researchers and manufacturers in advanced polymer science, particularly those developing functional materials for biomedical applications, coatings, and specialty additives. The product is supplied with the CAS number 925232-64-0.

Application

• Controlled/Living Radical Polymerization (RAFT Polymerization): As a key chain transfer agent for synthesizing well-defined polymers with complex architectures.
• Bioconjugation and Protein Modification: The activated NHS ester moiety facilitates efficient coupling with primary amines, useful for labeling proteins and creating polymer-biomolecule conjugates.
• Synthesis of Block Copolymers: Enables the production of di-block, tri-block, and multi-block copolymers with precise block sequences for advanced material properties.
• Functional Polymer Synthesis: Used to create polymers with specific end-groups for further chemical modification, enhancing compatibility or adding reactivity.
• Surface-Initiated Polymerization: For grafting polymers from surfaces to create smart coatings, non-fouling surfaces, or sensor platforms.
• Nanoparticle Functionalization: To tailor the surface chemistry of nanoparticles for improved dispersion, targeting, or reactivity in composite materials.
• Academic and Industrial R&D: A critical reagent for research in polymer chemistry, material science, and nanotechnology.

Basic Information

Item	Details
Product Name	n-Hydroxysuccinimide 2-(Dodecylthiocarbonothioylthio)Isobutyrate
CAS No.	925232-64-0
Molecular Formula	C21H36N2O4S3
Molecular Weight	500.73 g/mol
Synonyms	NHS-Dodecyl RAFT Agent; 2-(((Dodecylthio)carbonothioyl)thio)-2-methylpropanoic acid N-hydroxysuccinimide ester; S-Dodecyl-S'-(α,α'-dimethyl-α''-acetic acid)trithiocarbonate N-hydroxysuccinimide ester; DDMAT NHS Ester; 2-(Dodecylthiocarbonothioylthio)-2-methylpropanoic acid N-succinimidyl ester; NHS-CTA; RAFT Agent CTA-NHS
EINECS	Contact for details

Quality Control

Our n-Hydroxysuccinimide 2-(Dodecylthiocarbonothioylthio)Isobutyrate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FT-IR, to ensure high purity and consistent performance as a polymerization control agent. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO, THF, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.