Description

tert-Butyl 2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate is a high-purity, protected heterocyclic building block of significant importance in modern organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly in the areas of central nervous system (CNS) and oncology research. It is primarily sought after by research institutions, custom synthesis houses, and pharmaceutical companies engaged in the discovery and process development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the construction of complex drug molecules, especially those targeting neurological pathways.
• Medicinal Chemistry Research: A versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for the synthesis of proprietary compounds and reference standards.
• Chemical Biology: Employed in the synthesis of chemical probes for studying enzyme function and biological mechanisms.
• Process Chemistry: Serves as a starting material or intermediate in the development of scalable, commercial synthetic routes for APIs.

Basic Information

Product Name	tert-Butyl 2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate
CAS No.	924869-27-2
Molecular Formula	C11H17N3O2
Molecular Weight	223.27 g/mol
Synonyms	5H-Pyrazolo[4,3-c]pyridine-5-carboxylic acid, 2,4,6,7-tetrahydro-, 1,1-dimethylethyl ester; tert-Butyl 5H-pyrazolo[4,3-c]pyridine-5-carboxylate, 2,4,6,7-tetrahydro-; 2,4,6,7-Tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester; Boc-protected pyrazolopyridine; tert-Butyl 4,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(6H)-carboxylate; Pyrazolo[4,3-c]pyridine tert-butyl carbamate derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.